-If you only get canned questions, run.
-If questions are machine gunned without any followups, run.
-If they're not paying attention [0], run.
I'm surprised to see that many of the answers here don't seem to mention that in order to detect an environment that won't suit you, you ought to have questions for your interviewers.
If the questions you're asking are canned, or _your_ questions are machine gunned, and you don't follow up on the responses of your interviewers you're missing out on an excellent opportunity to get a read on what it's really like to work there. I'll grant you that reading people is not a science, but if don't go any deeper than "So what's it like to work here?", you're missing a big opportunity.
Make your questions unique, so your interviewer has good reason to pay attention. Don't just hit the softballs and nod. If they give you a vague answer, try to get them to be more specific.
For example, follow up "How are team successes and failures treated at $COMPANY?" with "Interesting. Could you give me an example of a specific situation where the team failed, and how it was dealt with?" with "Do you think it was the right response? Do you think there's any room for improvement?"
-If the interviewer[s] lacks empathy, it's a sign
somewhere up the chain that something's not right.
I believe this up to a point. As I said before, getting a clear read on someone you've just met is not always going to be easy. Yes, I believe it's a positive sign when your interviewer displays some level of empathy during the interview, but not everyone puts it out there. Don't make the mistake of thinking you know _exactly_ what the other person was thinking, or how they were feeling.
I think a lot of this comes down to going with your gut. Sometimes things are not exactly as advertised, so another piece of advice I'd give you is: Don't overthink it. Human beings have evolved to detect when something is, you know, "a little off". Trust yourself, but attempt to verify.
Finally, if you aren't in a rush, I've almost always been given the opportunity at the end of the interview to "reach out with any additional questions". Let the interview simmer for a day or so, and then take them up on their offer. Think about where you might have seen some hesitation, bases you may not have thought to cover in the initial interview, and see how they respond.
Trying to be clever in detecting a bad workplace neglects one of the most powerful tools at your disposal, your ability to ask questions that'll reveal whether it's a good place for you or not.