Reddit: IAmA grad student who has tried nearly every "study"/"smart" drug
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Of course, it's not hard to get a prescription if you want one. I just wish everyone didn't have to play this game of off-label prescriptions and lying to doctors.
Edit: Disclaimer: I take modafinil and I find it very useful.
So why not allow healthy people to take it? Because it distorts the competition - not who studied the most wins, but he who enhanced himself best. If you allow some enhancement, why not others forms? What about artificial limbs for athletes? Where does enhancement stop? What about everyone then feeling pressured to enhance themselves to still be able to compete, if they want to or not?
I don't think the sports analogy maps. Sports are artificial competitions and usually zero-sum. Commerce is cooperative. Intelligent individuals often benefit the less lucky. They invent new technologies that end up helping everyone.
If you allow some enhancement, why not others forms?
My sentiments exactly.
What about artificial limbs for athletes?
I guess that would be the Paralympics, but I don't have a problem with it. Cyborg kickboxing sounds more interesting than any modern day event.
Where does enhancement stop?
Hmm... matrioshka brains I guess. Although I'm willing to compromise and limit people to Jupiter brains.
What about everyone then feeling pressured to enhance themselves to still be able to compete, if they want to or not?
The same can be said for getting a college degree or some other kind of certification. Yes, people feel bad when they have low status, but the benefits of enhancement technologies outweigh the costs. I'd rather live in a world where Einsteins were 1 in 10. That world would have a better chance of solving humanity's problems.
Sports is all about artificial restrictions. Not just banning drugs, but banning certain moves and behavior. That's what makes it a sport, and not real life. The idea is to see what people do under controlled conditions.
Now, exactly what those restrictions should be is a useful question. But the existence of restrictions in sports is a given, by definition.
"What about everyone then feeling pressured to enhance themselves to still be able to compete, if they want to or not?"
That's how it's always been. Modern drugs are new, but the idea of self-modification to improve one's lot in life is not. Dressing better, having a better build, being more handsome or beautiful, being (or seeming) smarter; all quite historic pursuits.
The world's a better place for it, overall.
Welcome to tautology club.
Millennia old beliefs are the source of many current traditions held by society (specially drugs and sex related). I would love for someone to prove me wrong or at least state otherwise.
I think most people wouldn't take such an interpretation of the Bible, but even if you did, your explanation doesn't line up with current societal mores.
There are many mind and body altering substances that are not only tolerated, but celebrated. Almost all of modern Western medicine is based on introducing substances or therapies to the body that alter the mind or body. Everything from cold medicine to antibiotics alters the body. There are also numerous mind-altering substances used, such as narcotics, anesthetics, anti-psychotics, and anti-depressants. All of these are fully embraced by the vast majority of people, as well as the medical establishment.
But even if we stay away from medicine, there are plenty of examples of accepted mind-altering recreational substances. Nicotine, caffeine, and alcohol are the most obvious, but there are many other less severe substances (look at the ingredients on some energy drinks). By and large, the use of all of these substances is accepted.
If it were simply the case that cultural history prevented society from accepting mind-altering substances, none of the above would be accepted. The explanation must be more complicated.
I live by that verse.
I think it's somewhat telling that the best success seems to be at high-pressure environments with fairly prescribed tasks, like law school.
Basti and Jouvet (1988) describe a suicide attempt using 4500 mg of modafinil; the suicidee survived with no long-term effects but temporary nervousness, nausea, and insomnia.
That's 45 doses of modafinil and she was fine afterwards. 45 times the typical dose of caffeine would be lethal. Sure, you can argue from ignorance about potential long-term effects, but that argument works for anything that wasn't invented before you were born. Based on the evidence we have now, modafinil appears quite safe.
Edit: You are the first reply that didn't start with "because." You broke the pattern! >:(
That is, if an acute overdose of modafinil is not lethal, then it is more likely that the drug is safe for long term use. An equivalent acute overdose of caffeine would cause ventricular fibrillation and death. Yet few people are concerned about caffeine's long-term safety.
Also, notice the side effects of modafinil overdose: nausea, nervousness, and insomnia. Side effects of caffeine overdose include hallucinations, psychosis, and rapid muscle breakdown leading to kidney failure.
Although modafinil's mechanism of action isn't well-understood, evidence points to it having a neuroprotective effect. See http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2654794/ . So if anything, it's probably beneficial in the long-term.
A good example might be fructose, which you'd have to try very hard indeed to overdose on, but seems to be a long-term chronic toxin with many unpleasant effects, the high LD50 and the advisability of taking it at all being quite unrelated, indeed opposing.
What I've found in the literature says that longer term studies on the effects of modafinil are needed http://www.ccjm.org/content/74/8/561.full.pdf (2007)
While the WSJ ran an article, http://online.wsj.com/article/SB1000142405274870327860457462... , pretty much saying that black coffee is at worst a wash health wise (though I do note that they said caffeine has a pro-obesity effect and Modafinil an antagonistic effect (it's wiki article says as much)).
My point is that, from what I know, coffee isn't that bad. What information do you have that counters my notion or that modafinil is worth the unknown risks? Preferably with citations, please and thanks. I'm very curious about this topic for obvious reasons.
Modafinil is an essential tool in the arsenal of any active start-upper. Get it. If you are anything like me you will wonder how you got by without it, and I am not kidding.
I've known others, too, addicted to stronger things. A friend of mine battled a speed addiction for a year. He could very much imagine getting by without it - in fact he quite desperately wanted to, he just couldn't. I would presume the same is true for many, if not most, addicts of heroin.
Anyway, my understanding is that modafinil is not a drug of physiological addiction. It's a tool that one uses to overcome certain physical limitations, if and only if that is required. Think of it as a headache pill, but for tiredness. Certainly that is how I and everyone else I know who uses it views it.
Now this is relatively indirect, but compare it with a situation when everybody at a company is easily able to pull 20 hour days in the week before launching a product. Even if you feel you don't really want to use drugs, can you?
1. If I feel particularly tired in the morning.
2. If I need to get a lot of stuff done in a short amount of time.
3. If I need to study or perform my best for others. (Mostly job interviews or important meetings.)
On average, I end up taking it about twice a week. For me it's basically caffeine++. It helps me think faster and stay focused.
There is no drug in existence whose effects are purely and unarguably beneficial. The availability of drugs also has a social impact which goes beyond individual safety or efficacy.
Of course, it's not hard to get a prescription if you want one.
That's assuming you can afford the doctor and the drug and are willing to be a liar. Or if you're under 18, assuming your parents choose to "enhance" you and you choose to accept "enhancement".
http://en.wikipedia.org/wiki/Nootropics#Nootropics_and_racet...
http://en.wikipedia.org/wiki/Piracetam
But, if you need a bit... it works for me. When I am hiking or skiing 3-4 times a week, I get a lot more done.
I don't know how to make my diet better.
Here's one better. It's a type 2 diabetes study that compared exercise against metformin against a placebo. The conclusions were so overwhelmingly in favor of exercise that the study was stopped early.
Two of four subtasks that reflect complex cognitive speed (Stroop color/word interference and Concept Shifting Test) showed main and interaction effects with age of aerobic capacity in a hierarchical regression analysis, accounting for up to 5% of variance in parameter score after correction for age, sex, and intelligence main effects.
Still, that study is rather weak evidence. The benefits could be relegated to preventing decline in older people. Anecdotally, I do feel duller on days when I don't run; even if I didn't, I'd still exercise. It helps me relieve stress.
In terms of general benefits, most people would be better off if they exercised more, not less. I mean it's not like fit people wake up one day, look at a mirror and see a firm, toned body with six-pack abs then scream at the sky, "Nooooo! Why me?!"
I agree that regular exercise, a healthy diet, proper sleep, and a good schedule is a great solution most of the time.
It really is habit forming, though once you fall out it's hard to get back in. After all, being lazy is habit forming too, and once you've stopped accounting for gym time in your day it can be hard to start squeezing it back in.
.. certainly not easy to kick sugar/bread/milk habit.
People without ADD experience significant benefits from using Adderall because it's an amphetamine--not because they have undiagnosed ADD.
Any amphetamine helps you think clearly through being more alert and ability to concentrate for longer periods of time.
What do you think is the percentage of academics using cognitive enhancers or similar stuff?
How can you not want to hack your wetware? Or at least not be curious about what may be possible?
I'm surprised more people aren't up on this stuff and trying things out.
Feed your head.
Self-selected sample, though.
This link was posted a while ago here on HN, I believe.
It's more information dense, though it has testimonials from far fewer people. (That is, just one person.)