The thing that gets me (and others) worked up is when people make sweeping generalisations regarding the causes and treatments of depression. No one likes being painted with a broad-brush, but it adds insult to injury when something that has caused me so much suffering is dismissed as trivial and easy to solve. I've spent more than a decade trying to treat my condition. It's not as simple or easy as most people think.
I guess it's also an issue of semantics: 'depression' is a very broad term that gets narrowed down in our minds, based on our own personal experiences. When I hear it, I tend to think of the more serious kind because that's what I've lived through: not leaving my house for two weeks, not showering, eating or sleeping for three days etc... I can understand why some others might think of it more like 'that time my goldfish died and I was sad': this is the fortunate extent of their experience of low moods.
Or maybe I just envy those without brain cooties...