-It only has 4GB of RAM, but that's been enough up to now. Most builds are I/O bound anyway, and the SSD is fast.
-I don't use an external monitor, as the high pixel density of the screen more than makes up for the small size.
-The 64GB can be limiting, but in some ways its been beneficial, as its forced me to actually pay attention to backups.
-These days, if I have a long-running/high-resource process, I just spin up a VPS and run it there.
I think Google was pretty prescient with the Pixel laptops. When this one isn't enough, I'll be upgrading to the 2015 model.