There is no reasonable interpretation of the All Writs Act (which regards subpeonas) that could be interpreted to force Apple to preemptively make their OS insecure. If they include a backdoor in future versions of the iPhone, or if the FBI discovers a vulnerability, then it is entirely possible that they could use the same precedent to force them to open the backdoor for them, or even give them a metaphorical prybar for the backdoor.
But the point is that Apple is rapidly moving towards (and in their opinion, has already achieved) a hard stop -- they no longer possess the technical capability to break a locked iPhone after the 5s. For a specific case, and a specific subpoena, there is no work that Apple can do to comply with the subpoena.
And, like I said, it seems clear that Comey understands this, and is not asking Apple to weaken security in the future, and I see no indications that he is asking for that.