It probably won't happen in V1 but yes, it's incoming. We'll be able to pretty much use whatever we want. When wasm was first announced Brendan Eich made this clear, and a lot of the JS-All-The-Things folks who bet their careers on it were upset.
I'm not sure why, if you like JS, people can keep on using JS indefinitely. My theory on programming is to use the language that I prefer, and worry about everything else secondary. For me that's Python. I've mostly avoided any deep dives on learning JS so it'll be nice to be a part of a budding Python web frontend community when the time comes.