Furthermore d3, typescript and jquery is javascript so the question is more like "do I need to learn how to use tools to make websites?" at which point it is kind of silly.
No javascript needed to make a perfectly functional, efficient and useful website. Maybe it doesn't fit into your description of a "real" website?
That is just not true. I am sure that most web developers don't know d3, svg (other than exporting it from a drawing program) or typescript.
edit: this might actually work for some people, once you can access dom elements directly, but for now it is meant for huge WebApps, like games in the browser
That said, this should allow you to target a canvas element, with minimal JS binder to wasm code... all logic including what gets rendered could be outside JS... but you'd have to think of and control all input/output, and there are other considerations for rendering performance.
If you make few more steps in that direction, you can simply write your own operating system, make native apps for it and then call it all "a website", because you can run it in a browser using e.g. this JS computer simulator https://copy.sh/v86/
We don't plan to do things for WebAssembly, we plan to make WebAssembly powerful enough that anyone can run their language VM :-)
There has been work released recently which allows programs to be compiled to native binaries if they aren't dynamically evaluating anything however.