If you're really looking to do something strange, you could ditch the mouse all togeter. That's what I've done on one of my laptops.

For some reason when i first set it up the touchpad didn't work, and need some driver or something. Instead of fixing it like a normal person, I said to me self "just go with it".

I found a browser (qutebrowser) that works by using just the keyboard, and use tmux/vim and other terminal apps for everything else. The scrolling in the browser highlighted weird stuff (since the mouse cursor was always in the middle of the screen), but once I found a way to set the cursor to the top-left of the screen when X starts (a command in .xinitrc), no more issue.

I still have a minor issue every once and while. Sometimes i'll browse around and see a code snippit, or just some text I'd like to copy-paste, or a link with a url I'd like to copy and I'm not sure how. That's really been my only downside of going mouse-free.