It makes me sad, because I live on linux and notetaking apps there are mediocre. The best I could find is keepnote.
Onenote is years ahead of everything else, but I don't want the vendor lock-in and the binary files that it produces.
Evernote moved to .NET 3.5 so no wine support. Bah!
With apps that support LaTeX, I can just type $, start typing math, and type another $ to go back to regular text. Sure, I'll have to type things like \int, but that's still faster than trying to find the integral button in OneNote.
Edit: fix typo.
If you don't like Emacs, you probably won't like Org, though.
For example in Word typing Alt + = \int^1_2 \sum^x_(x+1) \ge \sqrt(25)
Would produce exactly what you would get in LaTeX.
You can even copy/paste between applications that support MathML.