Using one of those newer Retina MBPs which one cannot be upgraded in any way. The only disk expansion for these is the micro sdhc card hack (like this: http://9to5mac.com/2014/05/23/three-hacks-for-adding-permane...).
On your model you can even opt for bigger main SSD and probably replace dvd with another SSD like this: https://www.ifixit.com/Guide/Installing+MacBook+Pro+17-Inch+... . Oh the sweet upgradeability! <3
I have plenty of disk space but my photography hobby is eating most of it and the first thing that gets thrown away is the 14 Gb vmdk (this time it's Windows 8.1 + IE11).
Next one is probably 8 gigabytes of MS Office 2016. How can Office eat 8 gigabytes? :D (Compared to LibreOffice's 700 Mb or Office 2011 1,3 Gb.
And why worry about the new IEs and Edge? Microsoft says they support standards and so forth ... ;-D