I tried the Truly Ergonomic keyboard and while it was innovative, it was hard to get used to the middle row and the build quality was not so good.
I ended up buying from WASD Keyboards and I absolutely love their product. Complete customization, a tenkeyless option, excellent build quality, the most durable key caps around, but familiar IBM style key placement.
This one seems to be something in between these two.
In my opinion, the most important ergonomic improvements are to buy a tenkeyless model and set the capslock to a backspace. Having a heavy keyboard with sturdy grips at the base is also important.
Exotic features like a split keyboard, matrix layout, and strange thumb controls are just annoying and non-standard. I also somewhat regret having switched to colemak, but not entirely.