Something I rather enjoy about Wine is that it supports 16-, 32-, and 64-bit applications all from the same prefix. Quite a nice advantage over Windows :)
It is the games from Windows 98 and XP era, many used some combination of GDI and DDraw that doesn't work at all on new Windows versions, DDraw emulation is mostly broken, and pity you if the game used DDrawEx (it was to mix DDraw with D3D).
For example I am currently trying to figure a way to play SimCity 4 properly, the game is too demanding to run in an emulator, so some kind of native implementation is needed, but it also uses DDrawEx, that is very poorly supported in all OSes except Windows 98, ME and XP (it doesn't work in XP contemporary NTs either).
I think this is the kind of games the OP is happy ReactOS maybe will implement... because for DOS games, DosBox is more than enough already in most cases (there are some exceptions, like Noctis that is incredibly CPU-intensive and runs at 3 FPS in DosBox).
https://appdb.winehq.org/objectManager.php?sClass=version&iI...
Regardless though, this would legally require you to acquire a licensed copy of Windows 98, which will only become harder and harder down the road. Unless Microsoft decides to "free" all legacy software at some point.
ReactOS and WINE solve this problem in a different way, by providing open source solutions that everyone can use, copy and archive without cost or consequence.
Or VirtualBox can sum several cores and simulate a single faster CPU?