I understand the perceived benefit of compositional eloquence that this may add (pretty much borrowing from Python) but as others have pointed out, this is incongruent to the design of Ruby as a language and how it treats the relation between objects and their methods. Additionally, you lose any compositional elegance you may have gained when you decided not to use:

  x not in y

and instead propose:

  !(x in y)

Seems like a zero-sum addition to the language to me.