I think this is a little bit ironic. One of Paul's YCombinator companies, Loopt.com is using Microsoft/IIS 6.0 and Paul has been touting them to be one of the best of his startup investments. I agree with you on this one Paul, Loopt.com is the only one that is actually doing something real.
Another startup that just caught Techcrunch attention (and apparently got financed because the company has a real business model) is Gigya (http://www.gigya.com/) and they, too, are using Microsoft/IIS 6.0.
I'm not saying that there's a strong correlation between Microsoft and your success rate, but I just find it ironic.
The rest startups seem to not to have their business models and hoping for a buyout. Actually that includes Reddit as well. If you read Aaron's blog and see how they're desperate to get a "deal" from PG.
Note: I assume Microsoft/IIS 6.0 = ASP.NET