^^^ so much this.
there's this implied assumption that everyone using an adblocker is lost revenue, but a lot of that is going to be shitty ad impressions that never lead to clicks.
like it or not, advertisers can't actually put a gun to my head and force me to click on an ad and buy anything.
even if its a targeted ad that manages to engage me (coincidentally this did actually happen this morning with an ad from one of the rare newsletters that i've allowed to be sent to my e-mail inbox) then it probably doesn't work the way with me that advertisers want it to. i managed to find a product that i was interested in, but it was too expensive for me. so i did a "brandX vs ..." search on google to find brandY and now i've bookmarked the product their competition sells which seems to be more in line with my budget...
if you want to 'game' my purchasing habits you'd be better off not advertising at all in the classical sense, but instead send your product to review sites and/or just buy reviews in order to saturate google results. however, when all i see is obviously bought off review sites i'll go looking for relevant forums and look for user threads. by far the best thing there is to have a social media presence and have a staffer that surfs through forum sites and answers questions.
plus, you know, just have a good product for a good price to get people talking well about it... i realize that's some fucking crazytalk there though...