If they lose significant eyeballs, they can't charge a premium for the ad space. With less premium, they make less money. With less money, they can't write the articles.
At least with ad block and non-adblock eyeballs, they could say we get "XXX"k traffic per day/month/year. Less traffic overall will be bad in the long run.
If there is any party that is aware of how many people on wired's web property are running an ad blocker it is the advertising networks.
Wired is not telling them that they get 'XXX'k traffic per time unit, they're being told what their traffic is and what percentage of them has an ad blocker installed.
The truth is, I can always just go outside. Go for a run, Go for a hike with my kids... collect some rocks, smash rocks looking for geodes, play catch, play hide and go-seek, cook, drink. All will be much better than me sitting on my computer reading articles on Wired.com
The people commenting here that Wired doesn't need to care about ad-blocking readers, are entirely ignoring this critical element. It's a big component of how new people get introduced to Wired.
One metric that is used to rank sites is the bounce rate. If ad blocking users simply go back to Google and look for another result, then they will get penalised by Google.