I don't like the notion of applying the "first-world problem" dismissal to things that aren't trivialities. It's one thing to laugh about how you have to get up from the couch to get a remote. It's another thing entirely to talk about major changes to one's career, wiping away years of their work, or the loss of something they care deeply about as a "first-world problem".
Sure, getting acquired might be a "good problem to have", but it doesn't make its toll any less real.