But I have to say: I consider myself pretty good with computers and even program here and there. Yet, for the longest time I was confused about what exactly "karma" stood for. I knew it was a measurement of some sort(hey what else can a number be?) but I'd no idea about what exactly having "more karma" means.
My point is that when you use such phrases, you are assuming a specific kind of audience. Use of karma for reddit(tech-focused) is fine; even for news.yc it's fine - but for a consumer website, you should be very careful about introduction of new words. And say you love the word karma so much that you insist on using it - in that case, have a page that clearly explains what karma is assuming that the user knows nothing about it.
Karma is just one example - larger point here is to be careful about use of individual words that may have a huge role to play in your website. Thing that triggered me to make this post is I saw another poster use "karma" on their consumer start-up(bad idea IMO).
This is a mistake that is so easy to commit. Heck we did it when we launched. A lot of our users that were playing songs on our site had no idea what "Jigg It!" button meant. After couple user mails inquiring about it, we put up a tooltip saying "Jigg It if you like it!". Suddenly more people were clicking on it.
--Zaid
Another thing to consider is that "priesthood" stuff. Users feel good for knowing stuff about your product that newbies won't know right away. There may be times when it makes sense to use unfamiliar lingo on your site.
From that perspective, using the word Karma with a number is utterly meningless :-)