Looks like that uses Clang/LLVM. Does it work with C++ libraries built with GCC or MSVC?
MSVC: probably not; Clang's MSVC ABI support is coming along well, but last time I checked there was no COFF support in the JIT. GCC on Itanium ABI platforms should be fine, although mixing C++ stdlib versions would be risky (primarily an issue on OS X).