MRI Scans of a person's brain
github.com
github.com
It's too bad we don't have a universal way of sanitizing all meta data from JPEGs, PDFs, Word files, and everything else at the click of a button. Something that's really simple and quick to use.
I'm aware that there are lots of separate little tools and hacks to deal with sanitizing or anonymizing, but I wish there were either a standalone tool that dealt with every kind of common file, or a "Sanitize" button that was a standard feature in every viewer, editor, or browser (when uploading for example).
i was aware of the privacy implications. i briefly looked at the data in osirix that i would be exposing and decided that it was worth it.
There are many anonymized datasets available on Radiopaedia. http://radiopaedia.org/ I've spent quite a bit of time studying neurological conditions on that site and on wikipedia. Those are more useful, but anonymized. I'm not sure that there are many healthy MRI datasets available there, which makes it more difficult to statistically model MRI data.
I'm hoping to use Nipy and Dipy to create visualizations of my brain. In particular, i'm hoping to recreate some of the Diffusion Tensor Imaging work in this talk by Ariel Rokem: https://www.youtube.com/watch?v=HdrSZtB0uX0. However, i'm not sure if my DT images are high enough resolution.
I also did it for philosophical reasons. I believe that all digitized information past and present will be inevitably become known & public post facto. It's the nature of information & knowledge in our technological world to distribute itself until the world converges on total information omnipresence. So if, in the end, all [digitized] information is known, then there is no point in hiding information. This is more of a philosophical viewpoint though. obviously it's impossible for all information to converge in this way.
But this is true even of our own minds. And if our mind can be digitized from our brain, this also has interesting security implications. If you've seen the show stitchers, then you know what i mean.
Under no circumstances was this done in the name of art.
Anyways....
Wait, what?
I'm pretty sure that's not how computers (quantum or not) work.
Out of curiosity, why point this out? It's obvious that you didn't do it for a number of reasons. Hundreds, in fact. So why art?
I also did it for philosophical reasons. I believe that all digitized information past and present will be inevitably become known & public post facto. It's the nature of information & knowledge in our technological world to distribute itself until the world converges on total information omnipresence. So if, in the end, all [digitized] information is known, then there is no point in hiding information. This is more of a philosophical viewpoint though. obviously it's impossible for all information to converge in this way.
This would be the end of freedom. I'll go into the reasons if needed, but the discussion has happened a few times before. Suffice to say, if you're not allowed to have privacy, then you're not allowed to be free.
Deeper freedom (that is, infinite potential) is inherent to being itself, but if what you're looking for is something more like diversity or novelty, then yes, that's contingent on perceptual subject-object duality.
The Distaster Recovery/Backup&Restore industry would probably disagree with you.
What strength MRI was used for the scans? 1.5T, 3T, 7T?
[1] github.com/timpx/scripts [2] github.com/the-virtual-brain/tvb-library
e.g. the Human Connectome Project is still working on capturing the macroscale connectome, that is, high level structures only. Recording the microscale connectome, that is, the neuronal structure, currently requires destroying the brain you're analysing.
Brain upload is a sci-fi invention; using a T1, DWI, fMRI, EEG and behavioral data to build a realistic model of a subject's brain is today's neuroscience.
I will echo this point. I don't think I've met anyone in the field of neuroimaging who sees mind uploading as plausible. There's simply too much noise in the data for that sort of thing. Even simplified simulations such as the Human Brain Project require so much computing power that modeling a single mind is prohibitive; I can't imagine trying to perform whole-brain emulation accurately and practically without incurring more cost than it's worth. Wetware is good enough for me.
This step from (1) to (2) is a common assumption that most people are unwilling to reconsider, but it's equally possible to reject bottom-up modeling and ask what are the high-level constraints on brain activity that shape and direct it. This is what we do with the data I mentioned (T1, EEG, etc).
But you want the dendrites, too, not just cells.
Almost all information, especially personally identifiable information has a temporal component to it.
For example, that record you posted opens the door for someone to find your (dcunit3d's) current address.
If you recently pissed someone off on the internet (even under a different username), knowing your current address would enable that someone to send a litany of irritating, potentially damaging stuff your way.
On the other hand, if one of your records from five years ago ends up public, the address listed on that record is most likely not where you are living now so it is of little immediate use to a would be attacker.
Another fairly well know example is the AshleyMadison hack. In that case, the recency of a given user's record on the site made the difference in whether the hackers were able to successfully extort money from the victim.
Humble neuroinformatics lab knave here. While it's nice that you've made your data available, you might want to reconsider including the PHI. Many researchers are not interested in your phone number / where you live past the recruitment stage, and even then that information is kept confidential in accordance with IRB policies and HIPAA. The only data that a researcher might want to know is whether there are any phenotypes associated with your data (e.g., autism, ADHD, other stable traits, etc) or, in the case of task-related data, when certain blocks or events started/stopped and for how long. Even with phenotyping data, we are very cautious about how we go about sharing since we don't want to violate anyone's privacy (see here: http://fcon_1000.projects.nitrc.org/indi/enhanced/sharing.ht...). This is very important for individuals with conditions that are stigmatized in society- we don't want to make someone's life worse by outing them as being autistic, bipolar or depressed for instance.
In light of what I've said above, I will also express my disagreement with your philosophy. I do not believe that is natural for information to converge to a single point- in fact, many corporations rely on information asymmetries to gain an upper-hand in the market. The internet may reduce such information asymmetry, but it is unlikely that it will eliminate it completely (unless humanity turns into the Borg and creates a hive mind). Indeed so long as human thought is decentralized with separate minds in separate bodies, information asymmetry will remain the default.
Moving along, I want to note that a chief goal of science is to seek truths that are generalizable to the population at large. A single DTI series isn't really useful for achieving that goal since you can't determine how it relates to scans from a number of other participants(i.e., a 1st-level analysis is not a 2nd-level analysis; a case study is not a wider truth about cognition). In that sense, it might be better to see if there is a databank willing to accept your scan and donate your data to that so that you could be part of a broader sample.
More pragmatically, you might also want to consider using the NifTI format for your data, since this is the format that researchers use when processing data in various neuroimaging suites (i.e., Freesurfer, AFNI, SPM, FSL, etc). You may also want to consider organizing your data according to the Brain Imaging Data Structure standard, as many datasets are moving towards this (http://bids.neuroimaging.io/) and software tools are being written to take advantage of this structure.
Finally:
Under no circumstances was this done in the name of art.
That doesn’t mean that it can’t contribute to art (:P)- http://www.neurobureau.org/galleries/brain-art-competition-2...
No but seriously - it was a big shock to see my brain in a picture. It is a really weird experience, similar when I saw myself for the first time on film. Maybe this is a normal experience for the current generation, but I hadn't seen myself on film before age 15. You have an image how you move, what you look like, but then you see this on film, and it's a total shocker. All these small movements you make, typical for you, and everybody around you knows them, except for you. So everybody else sees nothing strange when viewing that movie, except you.
I've seen many MRI scans in films and tv series, although I can't remember one since then. From these I have a general picture of what a brain looks like. I've seen plastic 3D brain models. And then I see my brain and it's so different. It's clearly me, no doubt, but still... Totally weird!!!
https://web.archive.org/web/20081205032710/http://www.runfat...
The national lung screening trial [1] which had on the order of ~25k CT scan patients and ~25k radiograph patients found 96.4% and 94.5% of the positive screenings to be false positives. This screening trial has been a large motivator for computer-aided detection, diagnosis, and characterization of lung CT scans (although work on this goes back to the 80s and 90s).
If you look at the fleischner guidelines [2], the key factors in determining follow up are patient background and nodule size and growth rate. There are secondary diagnostic characteristics that are correlated with malignancy as well, e.g. spiculation and texture patterns.
[1]: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4356534/ [2]: http://radiopaedia.org/articles/fleischner-society-pulmonary...
It seems like that would be the case, but there has been talk about patenting parts of the DNA in the past, and legally sometimes things work in un-expected ways.
EDIT actually, it looks like I'm wrong in more states than I am right:
http://www.healthinfolaw.org/comparative-analysis/who-owns-m...
However, there are very strict rules on how that data can be used and shared.
Most of the HN crowd (and myself) would probably say that the ideal situation is for patients to own copyright and other rights in medical data generated about them, but I don't think this issue has actually been settled, either in a cultural or a legal sense [2].
[1]: http://www.hhs.gov/hipaa/for-professionals/privacy/guidance/...
There are some regrettable examples of cells and tissue being taken from patient specimens without their knowledge, some of which give birth to entire fields of research, and then it is later unclear whether data that could re-identify the patient's family (like genomic data) can be published [1]. It can be really hard to fully de-identify imaging and molecular data.
[1]: http://www.nature.com/news/deal-done-over-hela-cell-line-1.1...
You don't need to get consent if the PHI is de-indentified and the data was obtained through a regular course of treatment (not a study). This is really important because hospitals can publish anonymized case reviews for rare disorders or perform chart reviews on patient outcomes (drug X produced Y outcome in Z patients with [some condition]). I read through a lot of these papers on a daily basis and can't imagine the state of medical literature if consent was needed for publishing this clinical data. Retrospective chart reviews are typically exempt from human subject regulations.
More info: http://wichita.kumc.edu/Documents/wichita/researchcompliance...
The cases of unauthorized cell lineages predate HIPAA and other health laws that would make such actions illegal today.
However, patients not owning their own health data makes no sense. What data could belong more to a person than their own health data?
I found a case in Canada, for example, about a hospital asserting ownership rights to a biopsy tissue sample.
Then remembered the DNA patentability case not too long ago as well:
https://en.wikipedia.org/wiki/Ass'n_for_Molecular_Pathology_....
https://meta.wikimedia.org/wiki/Wikilegal/Copyright_of_X-ray...
Mine looks like any brain to me (no tumors, yay!).
From the DTI I was able to calculate the white matter trajectory with slicer: http://screencast.com/t/yDYFJdL7D
(I was a little let down I couldn't follow the visual nerves, but as they cross there is no clear direction of diffusion that could be imaged I guess...)
I added my email to my profile.
https://www.mypacs.net/mpv4/hss/casemanager
(30,380 cases. 187,945 images.) its a teaching/sharing site for radiologists where they can send the data from their PACS. this is the free public site which includes a basic web based dicom viewer to zoom/pan/window level etc
Though I'm not sure how much of it can be accessed without an account.
Here's a lot of data from Russ Poldrack, who scanned his brain and collected behavioral and metabolic data from himself very regularly over the course of a year: http://myconnectome.org/wp/data-sharing/
Example on http://1.bp.blogspot.com/-LuLV6F-Fp0o/TbcY7BUvpjI/AAAAAAAAAM...
With a usual MRI, unfortunately slices are too far apart to be able to stitch them together like this.
I have to keep myself up-to-date, it's been a while since I played with that!
Look for research groups in your local institutions and send an email to a couple grad students asking about studies they or their colleagues are running in the near future. A researcher may give you the scan if you ask nicely and say it's for personal interest, plus you'll be compensated for your time /and/ simultaneously help with the advancement science :)
thanks for tweeting me earlier. i had no idea this was on Hacker News! lol
https://www.claripacs.com/a.php?a=vw (Click and drag to scroll. "Share > Download" to download the full DICOM data)
This site has thousands of anonymized MRI and CT images of normal and abnormal scans, with clinical history in many cases. For example, here are annotated scans of normal anatomy:
https://www.claripacs.com/folder/Anatomy&view_type=-1
One challenge with writing web DICOM viewers is the lack of full 16 bit image support in browsers. This requires writing custom code to properly handle window / level on 16-bit medical images.
Disclosure: I'm a co-founder of Claripacs.
I suspect this is true for pretty much anyone in any field.
Digitizing a static physical model of the brain is problematic in itself. Many regions and structures in the brain are likely structurally dynamic. That is, the neural circuitry could change structure from day to day and this is definitely true over longer timescales. So it'd be much easier to read the data from the brain into another format rather than emulate the physical structure of the hardware.
I've thought a bit about information could be read from MRI scans such as these. In the absence of higher resolution data, I don't think there could any memories retrieved. I don't know the low-level details of how MRI data is encoded, but I do know it is recorded in slices. To retrieve memories, you'd need to read 3D regions from the brain. And it'd need to be much more high-resolution.
3DSlicer [2] is an excellent alternative that runs on Win/OS X/Linux
[1] https://ivmartel.github.io/dwv/demo/stable/viewers/mobile/
It's freeware (though not open source) and an excellent and fast image viewer. You'll have to also download the plugins to view the Dicom images (the MRI images). Fortunately all plugins for IrfanView can be downloaded as a single file as explained at the site above.
As other have already mentioned, the MRI images are full of personal meta data (which can be shown by clicking "info" in IrfanView). I assume that the OP must have been aware of this.
Very useful when I did my undergraduate thesis.
includes case analysis on the images
https://d0921abcf0d58ba49c3d-6ecbc7565855acc8ab3c742259f09fe...
http://www.nature.com/neuro/journal/v17/n11/fig_tab/nn.3818_...