> GUID generation algorithm 4 fills the GUID with 122 random bits. The odds of two GUIDs colliding are therefore one in 2^122, which is a phenomenally small number.
Another thing to consider, is that due to the birthday paradox once you build 2.7 * 10^18 GUID, the probability that you have at lest a collision is bigger than 50%. And 2.7 * 10^18 is only 2^61.2.