We have already gotten rid of the factory worker and that has led to withering away of Middle America. Removing the truck driver would be a huge nail in the coffin of Middle America. (If lab grown meat + vertical farming takes off, we can potentially drastically reduce the number of farmers in this country.)
I am all for these technical innovations, but we must be aware that this can dramatically change the economic/political/social landscape. Radical regressive ideologies spring out of such environments.