Several streaming services have native apps on both mobile & desktop. I think that their mobile apps could run pretty well on desktop.
For many complex apps though (like anything dealing with text edition), the lack of hover & right clics handling would be a pain. Android supports 'hover' events (and since API 1 IIRC) but nobody implements them in custom widgets.
Android supports mouse input but even as an android engineer I have no idea what the right click does in that situation.