I think you meant "white on black" is irritating.
People with astigmatism (aproximately 50% of the population) find it harder to read white text on black than black text on white. Part of this has to do with light levels: with a bright display (white background) the iris closes a bit more, decreasing the effect of the “deformed” lens; with a dark display (black background) the iris opens to receive more light and the deformation of the lens creates a much fuzzier focus at the eye.
Source http://blog.tatham.oddie.com.au/2008/10/13/why-light-text-on...