Yes. My favorite was a Coyote Point load balancer bug. If the last character of the HTTP options is "m", the connection will not get past the load balancer.[1] I found this because a web crawler was having trouble with one site. Fortunately, I knew someone with their own Coyote Point load balancer, and was able to establish that the connection went into the load balancer and never came out.
The load balancer has a big file of rules which contain regular expressions. Somewhere, I think there's a "\m" where they meant "\n". Reporting this to the vendor, along with a Python program to demonstrate the problem, was of course futile; they suggested "upgrading the software". I demonstrated that the bug existed on their own load balancer on their own site. I finally added a completely useless field to the HTTP header so that the last character was not "m".
[1] https://www.webmasterworld.com/webmaster_hardware/3312997.ht...