Just the other day I started with https://github.com/fortruce/react-fullstack-skeleton/ as a minimal skeleton for a new project of mine. Having not developed with "modern" Javascript yet, and only having used React by itself this was quite a convenient way to get started. Most other skeleton projects were too much, too huge for my taste when getting started.

It has:

* react-hot-loader which causes your changed to get automatically loaded into the running webpage

* Webpack, gulp and redux all set up

* A sample api server integrated in the development process to be used with a SPA

* SASS/CSS loading, which also gets hot loaded into your page (once/if my pull request is merged)

* Production builds with minifying and no sourcemaps (once/if my pull request is merged)

I'm not entirely happy with the structuring, but that can always be changed once you're familiar with the technologies. I also just submitted pull requests to address the issues listed in the readme.