Perl6 is such a completely different language and implementation that calling Perl5 is no different than calling Ruby or Python -- they all involve effectively embedding or calling out to the other language.
Here is a gist where I'm calling out to some Python. It is not done in the magical future way (which is in progress) of just doing "use matplotlib::pyplot:from<python2>" or similar, but not too bad.
https://gist.github.com/awwaiid/ef3f0abcfa96e34977b4
(I wrote this some months ago -- it can be a bit cleaner now)