A New Microscope Can See Inside Moving Cells in Real Time (2014) [video]

I think the title of this post could reflect that this article was published in 2014.

If you want to see more videos, the supplementary section of the article has quite a few with descriptions: http://m.sciencemag.org/content/346/6208/1257998.figures-onl...

Here's a fascinating talk by the Nobel laureate behind this technique, titled "Imaging Life at High Spatiotemporal Resolutions": http://youtu.be/2R2ll9SRCeo

...and so can an old microscope. Betzig invented PALM, which was a cool idea. This isn't. The lattice light sheet is a combination of a great idea Betzig didn't invent (light sheet microscopy) with another great idea Betzig didn't invent (structured illumination microscopy). The engineering is well done, but the fundamental idea is crap: the two techniques don't combine in an elegant way, and interfere with each other's strengths. What Betzig did exceptionally well with this paper was parlay a star-studded author list and some fancy surface-rendered time lapse movies into an extremely high-impact paper, despite a mediocre underlying accomplishment.

Here's the full paper:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4336192/

Can he make a GoPro for a sperm?