I really don't like multi-column layouts. It's impossible to read. arstechnica is a really good example. There are three columns, each with blocks that are different sizes.

So, I end up reading all the headlines from the left column, scrolling back to the stop, reading the second column, then scrolling back up for the third column.

I've tried to use Google+ on my Android device and the experience is awful. You get a few words and a huge picture that doesn't tell you anything about the post.