I lived a situation like yours, after I left from big consulting company, where you are in continuous contact with your your customer and other many people. I'm not introverts, I like to meet and chat with people and I've played many sports also as pro.

But after I decided to change my job, I went back to live with my parents in my city. I started to work at home. I'm honest I've made many mistakes, just for I had not experience. The results were just immediate:

* Do not discern work place and house

* Have no desire to go out. I remind that going out for me had become very hard, maybe for laziness, I don't know.

* Personal relationships very bad. Having relationships with friends or girl friend is not simple. If you stay all day at home with only your pc, you degrade your ability on cultivate relationships.

I've made similar choice to yours, I've took an office with my friend and many things are changed, I back to gym I start to meet many people each day. But I continue to work as remote position :)

Indeed the problem is not the remote work , the problem is your job location. In my experience, take an small desk in an open office or a room with a friend is a good choice, and it solved many problems for me.