It's possible to eschew the DOM even today with just JavaScript & <canvas> [0]! While this would be possible with wasm & WebGL as well, we're working to build something that integrates well into the open web platform. Check out #3 from our high-level goals [1].

[0]: https://github.com/Flipboard/react-canvas [1]: https://github.com/WebAssembly/design/blob/master/HighLevelG...