1. The liquid must be delicious (ie. not water) and almost covering or just barely covering your meat. It must also fill the crock pot at least half way. Think tomato sauce or stock.
2. The meat must be browned well before throwing it in the slow cooker. Fry the outside edges at high temp first.
3. Using well used muscles results in far better flavour -- rump, blade roast, flank, shank, and chicken thighs. Fat (but not toooo much) is your friend. It will dissolve over time and add flavour.
*. If you throw in a parmesan rind all your dreams will come true.