I'd be all over this if they supported yubikey's U2F. I love 1pass, but it always makes me uneasy using Dropbox (or anything similar) for syncing.
With traditional two-factor authentication, an existing device is used to authorize a new one. But the existing device is only used for authorization. The one-time passwords are not used to harden the encryption.
Your Account Key works in much the same way. It is required to authorize a new device. However, your Account Key is actually used to improve the encryption of your data. Both your Master Password and your Account Key are required to decrypt your data.
More in that article. :)