I was actually planning on testing a 33% deployment this evening, I guess what I'm really wondering is that because this is a low-level networking adjustment that modifies locking behavior, are there 'gotchas' I should be aware of beforehand?

I'll test and report back regardless; only afraid of the scenario where the test goes well, and the entire network goes down a week later (e.g., a wonderfully-fun time we had previously chasing down rogue epoll queues and zombie processes that only occurred after a threshold of sustained load).