Anthrax has no utility beyond criminal activity, and honestly I would consider anything that utilizes anthrax in that way to be criminal at all; thats terroristic. Crime is extrinsically motivated, terror intrinsic, and the use of Anthrax can only be physical harm, there is no greater reward to the applier.
But Megaupload is a tool that lets us share ideas and forms of art that people in some parts of the world may not have had the opportunity be exposed to otherwise. Even if it can be used for crime, that is not the only function it is capable of performing. Megaupload is exactly the model for products we should be building, because the sharing of ideas helps elevate us as a society. The minor and short term side-effect of piracy is irrelevant.