This sort of discrimination is not limited to Taxi Drivers,
Speaking from experience, Uber drivers can and will reject a customer if they don't like the neighborhood you're traveling to.
Interesting! Is this just to get a fare estimate? I don't think I ever noticed this feature in the app back when I used it.
This is especially true when the address contains difficult or uncommon words like Sycamore or Cheswycke, which I'm pretty sure I'd screw up writing, and I'd guess that others would as well.