As I understand it, there's plenty of ups and downs in a new venture, especially e-Health where you're somewhat at the whim of government (most countries' health systems are highly government regulated) and there are already plenty of past-failures, even one by Google. But surely the investors would already have been aware of that, and had decided to take a risk, because e-Health is also inevitably going to be a very big market eventually (just who knows when the ducks will finally start to line up), and if they want to play in that space they have to try.
But it seems this entrepreneur had last-minute cold feet at even the thought of the hurdles they will encounter.
It's that question -- whether this team has enough perseverance to stand a chance in that stormy sea -- that seems to have been answered at the last minute. The investors already knew the chances would be low.