Malaria protein could be an effective weapon against cancer

independent.co.uk

26 pointsnav3 comments

Odd, I posted this exact link yesterday[1]. I always thought there was link normalisation on HN?

[1] https://news.ycombinator.com/item?id=10390791

The full text of the study is paywalled here: http://www.cell.com/cancer-cell/abstract/S1535-6108%2815%290...

Fortunately the summary there has some useful information: "rVAR2 (recombinant malarial protein VAR2CSA) fused to diphtheria toxin or conjugated to hemiasterlin compounds strongly inhibits in vivo tumor cell growth and metastasis"

Anyone know how they're attaching those toxins/compounds to the malarial protein?

>how they're attaching those toxins/compounds to the malarial protein?

curious for the same, googled "protein fused to toxin" and it brought like this

https://en.wikipedia.org/wiki/Immunotoxin and http://www.ncbi.nlm.nih.gov/pubmed/8105849

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