It could, but it would require a compatible budget. Now how many companies that develop software (so I include the myriad of financial, healthcare, etc companies that create their own enterprise software) would do that? For example, take Bloomberg that develops the famous Terminal. How much software engineering is in that product (I can't tell, I never worked for them) but I would guess it is much less than DO-178C. So "acceptable" can mean one thing for the academic community and quite another for the real life companies.