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That'll save me from typing ⌘+^+⇧+4 and having to manually align the box.

Isn't it just ⌘+⇧+4?

Adding Control puts it in the clipboard instead of a file on the desktop

Yep. Then I can paste it into Imgur, the GIMP or Twitter.

I have this script bound to cmd-shift-6: https://github.com/jomo/imgur-screenshot