The Adblockers will lose horrifically. It will be worse than wack-a-mole, similar to the file-sharing industry's futile attempts to keep music free and shareable...
I now pay more per month for music than I did at any other time in my life, and I am becoming locked in to paying more per month forever. The music industry has won, they've replaced their old business model with one that costs us more while they take less risk.
Some people really dislike the idea of ads. They install adblockers. Publishers who make their living from ads respond. Who has more motivation, those who are vaguely annoyed, or those who lose their jobs and companies if they fail? The latter, of course. They will find a way around this because they have everything to lose.
I dislike the IAB, it's a force against progress within the ad business. But they're not going to lose horrifically, and even if they lose slightly it won't mean that you have won, just like with music.