No we go "hmm that might fuck something up; let's try it on a test VM" or at the very least google and see if anyone else has any problems.
You could also just wait a week for anything noncritical to allow others to flush out any issues, which is a more time-efficient strategy than manually reviewing gobs of KB articles.
For most people, disabling auto-update is a horrible strategy. If you have a central team actively managing updates with WSUS, you can get away with this. For the vast majority of people, turning off auto-update just means they stop installing updates at all, which is the reason auto-update is the default.