* Microsoft sells large parts of itself in order to be able to focus on its core competencies (just like IBM did)
* Someone will make an actually usable e-book reader.
* During the second half of the decade, the Chinese bubble will burst. This will be a quite heavy shock. A lot of people will lose a lot of money. A younger/more populist group of politicians will assume power in China.
* Brazil will become a real powerhouse.
* Hugo Chavez & his friends will be removed from power in Venezuela.
* Still no Duke Nukem Forever.
* 'Minimal Techno' will finally die / go out of fashion.
* Lady Gaga will be the new Madonna.
* Functional programming / dynamic languages will go out of fashion. People still using them will be judged as incompetent programmers by the people who moved on to the new fashionable programming paradigm(s). At the same time, huge corporations will embrace functional programming / dynamic languages and third world universities will start focusing on them in their courses.
* Google will experience change in management. From there, it will be downhill for them (at least for the rest of the decade).
* Surprisingly enough, Apple will still stay relevant even though Steve Jobs will have to leave his position due to health problems or something else.
That's what I could come up with off the top of my head. Feel free to disagree / rant / do name calling, this is not a serious thread anyway.