NASA starts year-long isolation to prepare astronauts for Mars
bbc.com
bbc.com
[1] "Other simulation experiments have taken place under the ocean off the Florida coast, in Antarctica and in Russia, where a 520-day Mars experiment was carried out in 2011."
They sure crammed a lot of days into that year.
Eight scientists lived in a closed biosphere to simulate what a potential colonization scenario might be like (among other things). The first experiment lasted 2 years, and encountered environmental issues, but also some psychological upsets - the crew split into two factions who became bitter enemies, among other things.