I use ScriptSafe (formerly ScriptNo) in Chrome similar to NoScript on Firefox. Also check out uMatrix.
Secondly, in order to achieve its goal, it's relying on a hack:
...
if (getElSrc(this) && getElSrc(this).toLowerCase().substr(0,11) != 'javascript:' && getElSrc(this).toLowerCase().substr(0,17) != 'chrome-extension:')
...
Not taking anything away from this extension, just that this illustrates what everyone's saying - concerns about reduced functionality.