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Comment by zastavka | Hacker News Reader

To be fair, the dosages most of these doctors are administering are well under a usual recreational dose, as the article mentions. IIRC you also build tolerance to ketamine pretty quickly, so I'd imagine the amount of K those people are doing that's causing bladder damage is a couple orders of magnitude larger than any of these patients.

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You don't get bladder problems using / abusing ketamine just at weekends.

People sniffing it every day / all day and getting through the 5grams+

But hammering that much every day of any drug is not a good idea.

At the above+1 commenter, take LSD at high doses everyday and see what damage you do to yourself

LSD is as close to as harmless a drug, physiologically, as you can get--no one has ever died of an overdose on it, and there isn't permanent physiological damage that happens even with regular heavy use.

Of course, your psyche might be another matter...

Agreed, not physically damaging. But it can destroy you mentally if used often and in heavy doses.

>but I've never heard of LSD destroying a persons bladder. That was the quote I was referring to. Bladder in tact, but a shell of a person left with severe paranoia and mental problems.

Not to hate on LSD, but no drug is safe is abused daily.

I'm not sure it's even possible to do decent quantities of LSD daily, at least in the context of trying to achieve a potent effect.

Plenty of times in my life I've done LSD and I learned pretty early on that it was pointless to try a dose the day after a previous dose.

It would just have very little to no effect on my mind and I would typically have to wait a few days at least before doing it again before it worked.

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