It also prevents you from doing things that only one RDBMS does (I was bitten by this because SQLite supports timestamps with timezone data and, at that time, the MySQL we used in production didn't) making your app more "robust" (you are using an ORM for a reason, right?).
Imagine you only test your app in PostgreSQL and, because of that, your app makes assumptions about the environment only PostgreSQL satisfies. You simply can't move to anything else without extensive rewriting. Now, when the workload changes, you can't just change your storage backend to one that suits your workload. You need to make PostgreSQL do whatever your new needs are. PostgreSQL is probably a good enough solution, but it's not the optimal solution for all problems.